Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) Selects TimeLogic DeCypher® to Accelerate Analysis of Superfamily Database

DeCypher speeds Hidden Markov Model investigations of Superfamily database

Cambridge, UK, and Crystal Bay, NV, July 16, 2002 – The Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) has selected TimeLogic’s DeCypher to advance their bioinformatics analysis capabilities.

DeCypher will allow LMB scientists to carry out new types of investigations which would be impossible without considerable computing power, including Hidden Markov Model analyses related to the Superfamily database (http://supfam.mrc-lmb.cam.ac.uk).

“We already have conventional computing resources,” explained Dr. Julian Gough of The MRC Laboratory of Molecular Biology, “but have installed DeCypher rather than expanding existing systems because we believe it is the best solution for dedicated HMM-based computing.”

Developed and maintained at LMB, the Superfamily database is a comprehensive public resource covering all proteins of known structure. Including over 7,000 Hidden Markov Models, it provides structural assignments to protein sequences and enables researchers to detect broader and more distant evolutionary relationships through sophisticated remote homology detection.

LMB plans to use its pair of Dell-based (NASDAQ: DELL) DeCypher servers to speed analysis of the Superfamily database using existing HMM techniques as well as novel techniques under development. The TimeLogic solution will enable the study of significantly larger data sets that would be impractical without DeCypher’s revolutionary bioinformatics performance.

“TimeLogic is delighted and honored to be selected by such an internationally respected institution,” remarked Jim Lindelien, TimeLogic’s CTO and Founder. “LMB’s critical bioinformatics tasks and larger experimental goals can be addressed efficiently by DeCypher while offloading rigorous analyses from the institution’s server farms. DeCypher’s proven price-performance advantage over conventional computers reclaims and extends the CPU capacity an organization already owns while simultaneously broadening research objectives. Given the realities of today’s tight budget constraints coupled with exponentially growing demands for biocomputing, DeCypher gets more done for less.”

About MRC
The Medical Research Council is dedicated to medical research aimed at improving human health. It supports research in academic, health services and pharmaceutical fields. MRC has funded projects that have led to some of the most significant discoveries and achievements in medicine in the UK. For additional information, please visit the MRC web site, http://www.mrc.ac.uk.

About LMB
The MRC Laboratory of Molecular Biology is one of the largest research institutes funded by the MRC. It carries out research into the fundamental processes of life by the study of the molecular basis of biological phenomena. For additional information, please visit the LMB web site, http://www.mrc-lmb.cam.ac.uk.

About TimeLogic
TimeLogic Corporation is dedicated to providing advanced computing technologies that extend life science research. Since 1996, DeCypher is the preferred solution for accelerated biocomputing™

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