Tera-BLAST™

Fast and Sensitive Nucleic and Protein Homology Searching

BLAST is a critical algorithm with broad applications from genome analysis to SNP mapping and proteomics research. With its heuristic design, it delivers results faster than dynamic programming methods such as Smith-Waterman. And yet the tremendous volumes of data generated by next-generation sequencing platforms can lead to days or weeks per BLAST search—even on a large cluster.

Several software implementations of BLAST exist from NCBI, Washington University and others. Tera-BLAST is a faithful implementation of BLAST software that executes on the TimeLogic FPGA-based SeqCruncher accelerator. Tera-BLAST derives its name the trillions (tera) of cell comparisons per second that can be accomplished on the TimeLogic solutions.

The Tera-BLAST algorithm suite is included with the CodeQuest workstations and is an available module for the DeCypher Enterprise solutions, where it complements the other sequence comparison modules, including HMM, SmithWaterman, GeneDetective.

Tera-BLAST Advantages:

• Provides the performance of hundreds of modern CPU cores
  in a small-footprint solution
  
  
• Higher throughput means you can complete better annotations with standard BLAST methods (BLASTN, BLASTX, TBLASTN, TBLASTX, BLASTP)
  
  
• Can be deployed in a desktop computer, or installed across a DeCypher cluster of 20 nodes
  
  
• "Nearly exact match" parameters enable anchoring on very small nucleic patterns (using nucleic wordsize as low as 4)
  
  
• Includes Tera-Probe for mismatch-tolerant high-sensitivity oligo searches
  
  
• Tera-BLAST delivers fast, affordable genome-scale analysis to your labor entire institution

Tera-BLAST™ Search Methods

Custom Benchmarks

Request a sample Tera-BLAST benchmark on your data today!