With over 600 next-generation sequencing instruments now deployed across both large core facilities and individual research labs, there is a flood of sequence data that needs to be analyzed and compared. Unquestionably, this ultra high-throughput technology is transforming genomics, but new bottlenecks in sequence alignment and downstream annotation are being created in the process. Our powerful field programmable gate array (FPGA) technology, SeqCruncher™, enables the DeCypher® and CodeQuest™ solutions to compare millions of sequences against thousands of genomic databases.

TimeLogic customers are implementing our applications for various phases of their pipelines, often for high-sensitivity remapping of short-read sequences to improve their mapping percentage, and for direct analysis of 454 data and assembled contigs.

Reference:

SLIPPER: An Iterative Mapping Pipeline for Short DNA Sequences, Lee Edsall- Ludwig, et al. (poster, ISMB 2008).