The DeCypher system is ideal for domain experts and for genomics specialists who are creating tools for data exploration and discovery. TimeLogic acceleration hardware is perfect for bioinformatics groups who don’t want or need substantial internal IT support. DeCypher enables you to quickly process comprehensive BLASTX searches of your gene sequences against a well-curated protein database of known proteins. For close matches, you can assume a similar protein function.

To reinforce your conclusions, it is possible to compare your protein sequence with an annotated Hidden Markov Model database such as PFAM. A match to a specific protein family can imply similar function, hence DeCypher’s HMM-Framesearch method is also available for automatic translation of your nucleic sequences and frameshift tolerant alignments while assigning protein families.

Reference:

Computational prediction and experimental validation of Ciona intestinalis microRNA genes, Norden-Krichmar TM et al., BMC Genomics 2007, 8:445 (29 November 2007).